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Auteur Arnich, N.; Abadie, E.; Delcourt, N.; Fessard, V.; Fremy, J.-M.; Hort, V.; Lagrange, E.; Maignien, T.; Molgó, J.; Peyrat, M.-B.; Vernoux, J.-P.; Mattei, C.
Titre Health risk assessment related to pinnatoxins in French shellfish Type Article scientifique
Année 2020 Publication Revue Abrégée Toxicon
Volume Numéro Pages
Mots-Clés Emerging marine biotoxins; Pinnatoxins; Risk assessment; Shellfish
Résumé Pinnatoxins (PnTXs) are a group of emerging marine biotoxins produced by the benthic dinoflagellate Vulcanodinium rugosum, currently not regulated in Europe or in any other country in the world. In France, PnTXs were detected for the first time in 2011, in mussels from the Ingril lagoon (South of France, Mediterranean coast). Since then, analyses carried out in mussels from this lagoon have shown high concentrations of PnTXs for several months each year. PnTXs have also been detected, to a lesser extent, in mussels from other Mediterranean lagoons and on the Atlantic and Corsican coasts. In the French data, the main analog is PnTX G (low levels of PnTX A are also present in some samples). No cases of PnTXs poisoning in humans have been reported so far in France or anywhere else in the world. In mice, PnTXs induce acute neurotoxic effects, within a few minutes after oral administration. Clinical signs of toxicity include decreased mobility, paralysis of the hind legs, tremors, jumps and breathing difficulties leading to death by respiratory arrest at high doses. The French agency for food safety (ANSES) recently conducted a review of the state of knowledge related to PnTXs and V. rugosum. Based on (i) the clinical signs of toxicity in mice, (ii) the mode of action of PnTXs as nicotinic acetylcholine receptor competitive antagonists and (iii) knowledge on drugs and natural toxins with PnTX-related pharmacology, potential human symptoms have been extrapolated and proposed. In this work, a provisional acute benchmark value for PnTX G of 0.13 μg/kg bw per day has been derived from an oral acute toxicity study in mice. Based on this value and a large shellfish meat portion size of 400g, a concentration lower than 23 μg PnTX G/kg shellfish meat is not expected to result in adverse effects in humans. ANSES recommends taking into account PnTXs in the French official monitoring program for shellfish production and identified data gaps to refine health risk assessment.
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ISSN 0041-0101 ISBN Médium
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Auteur Bodin, N.; Lesperance, D.; Albert, R.; Hollanda, S.; Michaud, P.; Degroote, M.; Churlaud, C.; Bustamante, P.
Titre Trace elements in oceanic pelagic communities in the western Indian Ocean Type Article scientifique
Année 2017 Publication Revue Abrégée Chemosphere
Volume 174 Numéro Pages 354-362
Mots-Clés atlantic-ocean; blue marlin; Environmental risk assessment; makaira-nigricans; Marine fish; Mediterranean Sea; Mercury; mercury content; North Pacific; risk-assessment; Seafood; Selenium; swordfish xiphias-gladius; Tuna fisheries' bycatch
Résumé The mineral composition of target and non-target pelagic fish caught by purse-seiners and longliners in the western-central Indian Ocean was determined. From the 10 essential elements analysed, selenium and zinc showed the highest concentrations in swordfish and blue marlin while Indian mackerel appeared as a good source of copper, iron and chrome. All catch had levels of lead and cadmium, two toxic elements, below the maximum sanitary limits. Although some concerns were raised regarding mercury concentrations in the largest species (wahoo, swordfish and blue marlin), molar ratios of mercury and selenium indicate that all oceanic pelagic fish from the western-central Indian Ocean are safe for human consumption. This study also gives insights on the relationships between the levels of essential and toxic elements in fish muscle and the size, trophic position and diet sources of the studied pelagic species. (C) 2017 Elsevier Ltd. All rights reserved.
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ISSN 0045-6535 ISBN Médium
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Numéro d'Appel MARBEC @ alain.herve @ collection 2119
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Auteur Parravicini, V.; Villeger, S.; McClanahan, T.R.; Arias-Gonzalez, J.E.; Bellwood, D.R.; Belmaker, J.; Chabanet, P.; Floeter, S.R.; Friedlander, A.M.; Guilhaumon, F.; Vigliola, L.; Kulbicki, M.; Mouillot, D.
Titre Global mismatch between species richness and vulnerability of reef fish assemblages Type Article scientifique
Année 2014 Publication Revue Abrégée Ecology Letters
Volume 17 Numéro 9 Pages 1101-1110
Mots-Clés Vulnerability; biodiversity; biodiversity loss; conservation; coral-reefs; extinction; fisheries; functional diversity; hotspots; macroecology; marine; patterns; protected areas; risk assessment; sensitivity
Résumé The impact of anthropogenic activity on ecosystems has highlighted the need to move beyond the biogeographical delineation of species richness patterns to understanding the vulnerability of species assemblages, including the functional components that are linked to the processes they support. We developed a decision theory framework to quantitatively assess the global taxonomic and functional vulnerability of fish assemblages on tropical reefs using a combination of sensitivity to species loss, exposure to threats and extent of protection. Fish assemblages with high taxonomic and functional sensitivity are often exposed to threats but are largely missed by the global network of marine protected areas. We found that areas of high species richness spatially mismatch areas of high taxonomic and functional vulnerability. Nevertheless, there is strong spatial match between taxonomic and functional vulnerabilities suggesting a potential win-win conservation-ecosystem service strategy if more protection is set in these locations.
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ISSN 1461-023x ISBN Médium
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Numéro d'Appel MARBEC @ isabelle.vidal-ayouba @ collection 630
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Auteur van der Oost, R.; McKenzie, D.J.; Verweij, F.; Satumalay, C.; van der Molen, N.; Winter, M.J.; Chipman, J.K.
Titre Identifying adverse outcome pathways (AOP) for Amsterdam city fish by integrated field monitoring Type Article scientifique
Année 2020 Publication Revue Abrégée Environ. Toxicol. Pharmacol.
Volume 74 Numéro Pages 103301
Mots-Clés Adverse outcome pathways; bioanalytical strategy; Biochemical & physiological biomarkers; biomarker responses; Ecological studies; eel anguilla-anguilla; environmental risk-assessment; Micropollutants risk assessment; oxygen-consumption; rainbow-trout; sole parophrys-vetulus; swimming performance; trout oncorhynchus-mykiss; xenobiotic-metabolizing enzymes
Résumé The European City Fish project aimed to develop a generic methodology for ecological risk assessment for urban rivers. Since traditional methods only consider a small fraction of substances present in the water cycle, biological effect monitoring is required for a more reliable assessment of the pollution status. A major challenge for environmental risk assessment (ERA) is the application of adverse outcome pathways (AOP), i.e. the linking of pollutant exposure via early molecular and biochemical changes to physiological effects and, ultimately, effects on populations and ecosystems. We investigated the linkage between responses at these different levels. Many AOP aspects were investigated, from external and internal exposure to different classes of micropollutants, via molecular key events (MICE) the impacts on organs and organisms (fish physiology), to changes in the population dynamics of fish. Risk assessment procedures were evaluated by comparing environmental quality standards, bioassay responses, biomarkers in caged and feral fish, and the impact on fish populations. Although no complete AOP was observed, indirect relationships linking pollutant exposure via MICE to impaired locomotion were demonstrated at the most polluted site near a landfill for chemical waste. The pathway indicated that several upstream key events requiring energy for stress responses and toxic defence are likely to converge at a single common MKE: increased metabolic demands. Both fish biomarkers and the bioanalytical SIMONI strategy are valuable indicators for micropollutant risks to fish communities.
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ISSN 1382-6689 ISBN Médium
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Numéro d'Appel MARBEC @ isabelle.vidal-ayouba @ collection 2753
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